This README.txt file was generated on 2025-02-19 by José Antonio Gómez Tejedor ------------------- GENERAL INFORMATION ------------------- Title of Dataset: Dataset of article Core-Shell Polyvinyl Alcohol (PVA) Base Electrospinning Microfibers for Drug Delivery Author Information José Antonio Gómez Tejedor Universitat Politècnica de València Camino de Vera s/n, 46022 Valencia (Spain) jogomez@upv.es Sofía Mares Bou Universitat Politècnica de València Camino de Vera s/n, 46022 Valencia (Spain) somabo@doctor.upv.es María Antonia Serrano Jareño Universitat Politècnica de València Camino de Vera s/n, 46022 Valencia (Spain) mserranj@fis.upv.es Principal Investigator: José Antonio Gómez Tejedor Date of data collection: 2025-02-19 Geographic location of data collection: Valencia, Spain Information about funding sources or sponsorship that supported the collection of the data: MCIN/AEI/10.13039/501100011033 grant number PID2020-114894RB-I00 General description: Datasets of electrospun membranes developed for controlled drug release applications. Both uniaxial Polyvinyl alcohol (PVA) and coaxial fibers with a PVA core and a poly (L-lactic acid) (PLLA) and polycaprolactone (PCL) coating were produced with different coating structures. The best conditions for the manufacture of the fibers were also studied and their morphology was analyzed as a function of the electrospinning parameters. Special attention was paid to the fiber surface morphology of the coaxial fibers, obtaining both porous and non-porous coatings. Bovine serum albumin (BSA) was used as the model protein for the drug release studies and, as expected, the uncoated fibers were determined to have the fastest release kinetics. Different release rates were obtained for the coated fibers, which makes this drug release system suitable for different applications according to the release time required. Keywords: electrospinning; coaxial electrospinning; Polyvinyl alcohol; controlled drug release -------------------------- SHARING/ACCESS INFORMATION -------------------------- Open Access to data: Open Licenses/restrictions placed on the data, or limitations of reuse: CC BY-NC-ND 4.0 Citation for and links to publications that cite or use the data: https://doi.org/10.3390/polym15061554 -------------------- DATA & FILE OVERVIEW -------------------- File list: 1-protocols/Protocols.odt Electrospinning fabrication protocols 2-characterization\FESEM\ FESEM images and data 2-characterization\FESEM\graficas.xlsx Histograms of fiber diameter distribution as a function of processing parameters 2-characterization\FESEM\Samples_FESEM_Microfibers Diamater Analyze.ods Fiber diameter measurement 2-characterization\FESEM\Readme.txt File naming information used in image subfolders 3-release\Fig14 y 15.xlsx BSA release data Type of version of the dataset: processed and raw data Total size: 303 MB -------------------------- METHODOLOGICAL INFORMATION -------------------------- Methodological information is given in article https://doi.org/10.3390/polym15061554